Claims of sex differences: an empirical assessment in genetic associations

Researchers are interested in determining how sex and other genetic traits interact in determining risk because if a particular genetic trait is a risk factor only for women or only for men, this information would be useful in disease screening. However, as a result, most papers that report on “sex-related differences in genetic associations” are not sufficiently supported, due to lack of control groups, comparing dissimilar cohorts of men and women and many other factors.